Comparison of ultra-low-dose versus standard-dose computed tomography for esophageal foreign body detection

Prospective comparison of ultra-low-dose versus standard-dose computed tomography for esophageal foreign body detection

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13588740

Enrollment

180

Registered

2026-03-31

Start date

2024-01-18

Completion date

Unknown

Last updated

2026-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients suspected of swallowing esophageal foreign body (EFB) Digestive System

Interventions

Patients will be randomized to ULD-CT (100 kV/50 mA, adaptive statistical iterative reconstruction-V 80% + deep learning image reconstruction) or SD-CT (120 kV/200 mA, filtered back projection + adap

Eligibility

Sex/Gender

All

Age

3 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 3–80 years 2. A history of foreign body ingestion within 6 hours of presentation 3. Symptoms suggestive of esophageal impaction, including dysphagia, odynophagia, chest pain, or hypersalivation 4. Planned endoscopic or surgical evaluation within 12 hours of CT imaging

Exclusion criteria

Exclusion criteria: 1. Severe cardiorespiratory instability requiring immediate intervention 2. Pregnancy or a positive pregnancy test 3. A known contrast allergy (for enhanced scans when clinically indicated) 4. Prior esophageal surgery or known esophageal stricture 5. Metallic implants causing substantial artifacts affecting >30% of the esophageal evaluation area 6. Body mass index (BMI) >40 kg/m² (due to potential image quality degradation at ultra-low doses)

Countries

China

Contacts

Public ContactXing Guan

guanxing_gx2024@126.com+86 (0)15932013616

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 17, 2026