Medial knee osteoarthritis Musculoskeletal Diseases
Conditions
Interventions
The randomization sequence was generated using specific software by an independent collaborator not directly involved in assessment of participants.
Participants in the experimental g
Sponsors
Faculdade de Desporto da Universidade do Porto
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Diagnosis of knee OA made according to the clinic and radiographic criteria established by the American College of Rheumatology. This comprises medial knee pain, radiographic osteophyte in the medial joint space of the knee and morning stiffness lasting ?30 min and/or crepitus during motion 2. Specific radiographic inclusion criteria are Kellgren & Lawrence grade 2 or 3 on a full-length anteroposterior radiograph 3. Age ? 50 and < 80 years old 4. Medial knee pain in the past week of =3 on Visual Analog Scale
Exclusion criteria
Exclusion criteria: 1. Symptomatic evidence of lateral compartment 2. Patellofemoral OA 3. Knee surgery within the past six months 4. Systemic arthritic conditions 5. Corticosteroid injection within the previous six weeks 6. Body mass index above 35 (difficult to accurately place motion capture markers) 7. Any other condition affecting lower limb function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| First peak external knee adduction moment measured by gait analysis at baseline and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Pain measured with visual analog scale at baseline and 12 weeks 2. Pain, other symptoms, function in daily living, function in sport and recreation, and knee-related quality of life, measured using the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire at baseline and 12 weeks 3. Physical function assessed using physical tests (30s chair stand test; 40m fast-paced walk test; stair climb test) at baseline and 12 weeks | — |
Countries
Portugal
Outcome results
None listed