How common is osteosarcopenic obesity syndrome (OSO) in an adult population?

Osteosarcopenic obesity syndrome

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13557768

Enrollment

125000

Registered

2021-12-17

Start date

2022-05-01

Completion date

Unknown

Last updated

2021-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteosarcopenic obesity syndrome (OSO) (obesity, sarcopenia, and osteoporosis) Musculoskeletal Diseases Obesity, Osteoporosis, unspecified

Interventions

This project has a cross-sectional design meaning that the participants will only be invited to testing once. Each testing session will last approximately 90 minutes. Overweight (BMI >25 kg/m²) women

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Overweight (BMI >25 kg/m²) women over 50 years 2. All adults (independent of age or sex) will be included from the biobank databases

Exclusion criteria

Exclusion criteria: Aged under 18 years

Design outcomes

Primary

Measure	Time frame
Bone mineral density, lean mass, and body fat measured using DEXA at a single time point	—

Secondary

Measure	Time frame
Measured at a single time point: 1. Muscle strength in isometric knee extension and grip strength 2. Muscle mass measured using DEXA 3. Physical performance (gait speed, handgrip strength, one-leg stance, and sit-to-stand chair) 4. Well-being, quality of life, work ability, mental health, physical activity habits, and nutrition habits (RAND-36, PROS, PROQOL, IPAQ- IPAQ, and SarQoL) 5. Muscle quality (muscle volume divided by the muscle force output) and degree of fat infiltration in the muscle measured using magnetic resonance imaging (MRI) of the quadriceps 5. Biomarkers of inflammation and bone turnover measured using blood samples	—

Measure

Time frame

Measured at a single time point: 1. Muscle strength in isometric knee extension and grip strength 2. Muscle mass measured using DEXA 3. Physical performance (gait speed, handgrip strength, one-leg stance, and sit-to-stand chair) 4. Well-being, quality of life, work ability, mental health, physical activity habits, and nutrition habits (RAND-36, PROS, PROQOL, IPAQ- IPAQ, and SarQoL) 5. Muscle quality (muscle volume divided by the muscle force output) and degree of fat infiltration in the muscle measured using magnetic resonance imaging (MRI) of the quadriceps 5. Biomarkers of inflammation and bone turnover measured using blood samples

—

Countries

Norway

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026