High-quality cell salvage in obstetric and gyneacologic patients with moderate to high risk of blood loss. Pregnancy and Childbirth
Conditions
Interventions
Autologous transfusion of blood cells salvaged by microfiltration technology
Participants in the intervention group will receive an autologous blood transfusion prepared by microfiltration cell salvag
Sponsors
National Blood Service Commission
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Undergoing obstetric or gynaecologic procedures 2. Ability to provide informed consent, direct or by a relative representative 3. Procedure with estimated blood loss of at least 500mL
Exclusion criteria
Exclusion criteria: 1. Sickle cell disease 2. Active malignancy contraindicated to cell salvage e.g. abdominal cancer 3. Excessive contamination of the wound field with bacterial contamination
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adoption of the autologous blood transfusion procedure measured using (1) surveys of the health care staff involved in the provision of the autologous blood, (2) autologous blood transfusion exam outcomes as recorded by the health care staff involved in the provision of the autologous blood and (3) participant enrolment rate, directly upon implementation and three months after implementation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Volume of autologous blood processed as read from the volume indication on the blood infusion bag upon completion of the autologous blood processing. Upon completion of delivery or surgical procedure, the total volume of autologous blood processed is calculated by adding the volumes of all autologous blood units processed. 2. Volume of autologous blood reinfused as read from the volume indication on the blood infusion bag upon start of the autologous blood reinfusion. Upon completion of delivery or surgical procedure, the total volume of autologous blood reinfused is calculated by adding the volumes of all autologous blood units reinfused. 3. Estimated volume of blood loss as read from the volume indication on the blood collection device before processing of each blood unit. Upon completion of delivery or surgical procedure, the total volume of blood loss is calculated by adding the pre-processed volumes of all autologous blood units lost. 4. Patient blood haemoglobin measured by blood gas analysis before the reinfusion of the first autologous blood unit and after the reinfusion of the last autologous blood. 5. Units of additional donor blood transfused counted after delivery or surgical procedure 6. Processed autologous blood haemoglobin level, red cell count, platelet count and white blood cell count measured by a hematology analyzer complete blood count upon completion of processing of each autologous blood unit | — |
Countries
Nigeria
Contacts
Public ContactAdetoun Kalejaiye
Outcome results
None listed