Psychosis Mental and Behavioural Disorders Psychosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Met criteria for being at clinical high risk of psychosis at some point within the previous 12 months of the commencement of the study and would have been under the care of the OASIS teams 2. Aged 16-40 years 3. Provide informed consent 4. Express interest in vocational/educational support 5. At least 12 months of treatment remaining with the OASIS team
Exclusion criteria
Exclusion criteria: 1. Unable to fully comprehend the purpose of the study or make a rational decision whether or not to participate (i.e. not 'Gillick competent') 2. Antipsychotic medication for > 30 days (cumulative number of days) in the 3 months before the baseline assessments (including self-ratings and screening assessments), at doses that would be adequate for treating a first episode of psychosis (i.e. excludes very low doses) 3. Any past episode of frank psychosis lasting > 7 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of the intervention assessed using: 1. Evidence of the acceptability assessed by interviews 2. Feasibility of delivering the intervention and conducting the research assessment assessed using data integrity 3. Willingness to be recruited, take part in the intervention and drop-out rate measured using consent forms and records 4. Number of eligible participants 5. Willingness to be re-assessed after the intervention (at every follow-up participants will be asked if they wish to be reassessed) 6. Standard deviation of the secondary outcome measures to estimate the sample size for the definitive trial 7. Research and intervention resources, including training and supervision, necessary for delivering the IPS intervention 8. Rates of employment/enrolment on educational course at 3 and 6 months follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| At baseline, 3 months and 6 months: 1. Symptoms of psychosis or attenuated symptoms of psychosis measured using the CAARMS 2. Self-efficacy measured using the General Self-Efficacy Scale 3. Functioning assessed using the Global Assessment of Functioning and Social and Occupational Functioning Scale 4. How participants use their time measured using the Time Use Survey (TUS) 5. Health and social aspects measured using the Health of the Nation Outcome Scale (HoNOS) | — |
Countries
England, United Kingdom