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Increasing the uptake of cervical and lung cancer screening with targeting

INSIGHT – Increasing Screening In Groups Hard to Reach with Targeting: Increasing the uptake of national screening programmes with smart targeting of low-uptake subgroups

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13515216
Enrollment
463000
Registered
2026-03-24
Start date
2026-08-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uptake of cervical and lung cancer screening Cancer

Interventions

This is a three-arm implementation trial with a quantitative evaluation using a randomised, parallel-arm design. Participants across the three arms will receive different invitation strategies. In Arm

Sponsors

Imperial College London
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 74 Years

Inclusion criteria

Inclusion criteria: 1. Registered with a participating GP practice. 2. Eligible for one of the NHS cancer screening programmes: For cervical cancer screening: 1. Aged 25–64 years 2. Have a cervix 3. Only individuals who have not responded to their initial national cervical screening invitation will be included For lung cancer screening: 1. Aged 55–74 years 2. Current or former smokers 3. All eligible individuals invited through the NHS lung cancer screening programme Targeted subgroups The targeted subgroups have been selected following a literature review and analysis of Fingertips data (https://fingertips.phe.org.uk/). The targeted subgroups for cervical screening include: 1. Women/People with a cervix with learning disabilities 2. Women/People with a cervix aged 25–34 years 3. Women/People with a cervix whose preferred language is not English 4. Women/People with a cervix aged 45–64 years living in more deprived areas For lung screening, the targeted subgroups are current smokers and former smokers living in more deprived areas.

Exclusion criteria

Exclusion criteria: 1. Not eligible for cervical or lung cancer screening based on NHS programme criteria 2. Not registered with a participating GP practice

Design outcomes

Primary

MeasureTime frame
Lung and cervical cancer screening uptake measured using screening attendance record at GP practice system at 1 month after the final invitation cycle

Secondary

MeasureTime frame
Lung and cervical cancer screening uptake measured using screening attendance record at GP practice system at 3-month after the final invitation cycle;Message delivery rates measured using digital tracking system, Messaging service delivery reports (number of successfully delivered messages ÷ total messages sent × 100) at immediately after message dissemination;Message click rates (percentage of recipients who clicked the booking link) measured using digital tracking system (clicks ÷ total invitations sent × 100) at the end of each invitation round. The interval between invitation rounds will be at least 1 week, depending on slot capacity;Appointment booking behaviour (Number of recipients who booked/declined/did not respond to an appointment) measured using digital tracking system at measured at the end of each invitation round. The interval between invitation rounds will be at least 1 week, depending on slot capacity

Countries

England, United Kingdom

Contacts

Public ContactGaby Judah
g.judah@imperial.ac.uk+44 2075941419

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 10, 2026