Marburg virus infection Infections and Infestations
Conditions
Interventions
This is a household-based cross-sectional survey using a two-stage sampling method. First, communities are conveniently selected and divided into clusters using population data. GPS coordinates are ra
some homes provide multiple participants. The approach ensures representative sampling and enables infection rate and transmission estimates.
If participants agree to take part, their basic informati
Sponsors
Kumasi Centre for Collaborative Research in Tropical Medicine
Eligibility
Sex/Gender
All
Age
10 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Individuals aged 10 years and above 2. Member of the visited household 3. Resides in household for more than 3 months before study start 4. Willingness to participate in the study demonstrated by a signed or thumbprinted informed consent or assent form
Exclusion criteria
Exclusion criteria: Known pathology or a health problem contraindicated with blood sample collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of MARV-specific IgG antibodies measured using Luminex Magpix -based multiplex immunoassay from plasma samples collected during participant enrolment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quantitative levels of pathogen-specific IgG antibodies against selected candidate WHO-priority pathogens, measured using Luminex Magpix -based multiplex immunoassay from plasma samples collected during participant enrolment 2. Correlation of antibody titers with potential exposure histories or risk factors, assessed using questionnaire-derived demographic and exposure data collected during participant enrolment. | — |
Countries
Cameroon, Guinea, Uganda
Contacts
Public ContactAlexander Owusu Boakye
Outcome results
None listed