Septic knee arthritis Musculoskeletal Diseases
Conditions
Interventions
The intervention involves serial aspirations and IV antibiotics. The involved joint will be prepped and draped in a sterile fashion before arthrocentesis. Aspiration of the joint will be done using an
Sponsors
Sultan Qaboos University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Informed consent to participate in the trial 2. Patient demographic data (Age, sex, knee side). Age 18yrs and above 3. Patients’ comorbid 4. Pre-aspiration data (Knee pain, swelling, redness, ROM actively and passively, WOMAC, VAS score, Inflammatory marker, Counts, Gram Stain and Culture results, Antibiotic if initiated before or after antibiotics) 5. Repeat labs every 48 hours by CBC and CRP 6. Repeat aspiration every clinical recollection noted and/or patient worsening in clinical/laboratory markers 7. Max aspirations are 3 times, then label as failed and proceed to standard washout 8. F/u 2 weeks, 3 months, and 6 months. Each with VAS and WOMAC functional scores
Exclusion criteria
Exclusion criteria: 1. Infected prosthetic joints 2. Adjacent osteomyelitis preceding joint infection 3. Septic arthritis occurs as an incidental event late in the course of an otherwise fatal illness 4. Patients that are 17 years old or less 5. Reactive or Inflammatory arthritis 6. Polyarticular joint involvement 7. Symptoms more than 1 week
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Failure of treatment and proceeding with standard surgical washout measured using laboratory methods for the inflammatory markers, C-reactive protein (CRP) and white blood cell (WBC) count at baseline, then every 48hrs for 10 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee pain and functional scores measured using a knee Visual Analog Score (VAS) and knee the functional Western Ontario and McMaster University Osteoarthritis Index (WOMAC) at 2 weeks, 3 months and 6 months | — |
Countries
Oman
Contacts
Public ContactHumaid;Humaid Al Farii;Al Farii
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Outcome results
None listed