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The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder

The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder: a single-blind randomised control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13453452
Enrollment
40
Registered
2016-05-25
Start date
2014-06-01
Completion date
Unknown
Last updated
2020-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adhesive capsulitis of shoulder Musculoskeletal Diseases Adhesive capsulitis of shoulder

Interventions

The control group (hyaluronate group) was injected only with hyaluronate (Hyal Shin Poong, PhD, Korea, 2.5-mL injection, 1% hyaluronan, molecular weight 940–1,020 kDa) five times in 1-week intervals.

Sponsors

Soonchunhyang University (South Korea)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who visited the Outpatient Clinic at Soonchunhyang University Hospital 2. Pain and limited movement of the shoulder joints

Exclusion criteria

Exclusion criteria: 1. Trauma 2. Stroke 3. Endocrine diseases 4. Arthritis in the shoulder 5. They had been administered an MAO (Monoamin monoamine oxidase) inhibitor during the past 2 weeks 6. They had hypersensitivity to opioids 7. They had received an intra-articular injection in the shoulder during the past 6 months 8. They had undergone other surgeries 9. They had been experiencing symptoms for more than 9 months 10. Ultrasonography showed a full-thickness tear in some tendons of the rotator cuff

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS), passive range of motion (PROM) of the shoulder joint, and Shoulder Pain and Disability Index (SPADI) scores were assessed at baseline and weeks 1, 2, 3, 4, and 6 after the initial injection.

Countries

Korea, South

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026