An investigation of proteins found in urine and blood to identify a combination of proteins which will detect bladder cancer

Evaluation and comparison of urine markers to investigate the development of a diagnostic index for bladder cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13449084

Enrollment

200

Registered

2015-02-06

Start date

2006-11-13

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haematuria in bladder cancer Cancer

Interventions

This study recruited 200 patients who had reported blood in their urine to their doctor. Half of these patients had a final diagnosis of bladder cancer and the other half had other diagnoses. Blood

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with haematuria who have undergone cystoscopy 2. Patients must be able to understand the study procedures and willing to give informed consent

Exclusion criteria

Exclusion criteria: 1. Patients who have not had a flexible cytoscopy 2. Patients who did not present with haematuria 3. Patients with UTI destined to undergo TURB 4. Patients currently suffering from clinically evident alcoholism and or drug dependency

Design outcomes

Primary

Measure	Time frame
1. To compare specificities and sensitivities of the TCCB markers and generic cancer markers in predicting TCCB 3. To retain a bank of urine and blood samples if the need arise to assay further markers 4. To determine the best combination of factors for a prognostic index for TCCB	—

Secondary

Measure	Time frame
To compare biomarkers as prognostic indicators for TCCB	—

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026