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A pragmatic cluster randomised controlled trial of a guideline-based educational outreach intervention to improve quality of adult respiratory care in South African primary care clinics: the PALSA (Practical Approach to Lung Health in South Africa) trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13438073
Enrollment
1999
Registered
2005-08-22
Start date
2003-04-08
Completion date
Unknown
Last updated
2015-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory diseases Respiratory Cough and/or difficult breathing

Interventions

Educational outreach to groups of intervention clinic nurse practitioners, based on a clinical practice guideline on integrated adult respiratory case management and delivered with accompanying suppor

Sponsors

University of Cape Town Lung Institute (South Africa)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Forty primary care clinics in a high tuberculosis and HIV burden province of South Africa (Free State). Data will be collected from patients 15 years and older who provide written consent and who present with any one of the following: 1. Difficult breathing on the day of interview or during the last 6 months 2. Current cough for 7 days or more 3. Recurrent cough in the last 6 months 4. Current cough and a temperature in excess of 38°C and/or a respiratory rate of 30 breaths per minute or more

Exclusion criteria

Exclusion criteria: Patients referred elsewhere urgently by their nurse practitioner will be excluded.

Design outcomes

Primary

MeasureTime frame
1. Sputum testing for tuberculosis 2. Inhaled corticosteroid prescriptions 3. Antibiotic prescriptions 4. Cotrimoxazole prescription among patients with tuberculosis

Secondary

MeasureTime frame
1. TB case detection 2. Mortality 3. Smoking cessation advice received 4. Smoking cessation 5. Readiness to quit smoking 6. Frequency and severity of respiratory symptoms 7. Health-related quality of life (Euroqol) 8. Health care utilisation 9. Cost of care

Countries

South Africa

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Apr 12, 2026