Early screening and warning on adolescent idiopathic scoliosis Musculoskeletal Diseases
Conditions
Interventions
This is a multicenter observational cohort study conducted under the National Key R&D Program of China (Grant No.: 2024YFC3507405), led by Wangjing Hospital of China Academy of Chinese Medical Science
Sponsors
Ministry of Science and Technology of the People's Republic of China
Eligibility
Sex/Gender
All
Age
10 Years to 18 Years
Inclusion criteria
Inclusion criteria: Subjects with adolescent idiopathic scoliosis: 1. According to the diagnostic criteria of the Scoliosis Research Society (SRS), scoliosis is defined as a condition where the Cobb angle measured on a standing full-spine coronal X-ray film is = 10°. 2. Aged 10–18 years. 3. Cobb angle between 10° and 45°, including mild scoliosis (10° = Cobb angle < 20°) and moderate scoliosis (20° = Cobb angle < 45°). 4. Risser sign grade 0–4. 5. Informed consent signed by the subject or their guardian. 6. No scoliosis-specific treatment received in the past 3 months. Healthy volunteers: 1. Cobb angle < 10°. 2. Aged 10–18 years. 3. Informed consent signed by the subject or their guardian. 4. No participation in other clinical studies in the past 3 months.
Exclusion criteria
Exclusion criteria: 1. Secondary scoliosis, such as congenital scoliosis and neuromuscular scoliosis. 2. Comorbidity with severe systemic diseases, including those of the cardiovascular, cerebrovascular, liver, and kidney systems. 3. Spinal lesions, such as fractures, tumors, and tuberculosis. 4. Mental illness or cognitive impairment that prevents cooperation with treatment and evaluation.
Countries
China
Contacts
Public ContactXu Wang
Outcome results
None listed