The effectiveness of harpagophytum procumbens cream in the relief of osteoarthritic pain of the knee

The effectiveness of harpagophytum procumbens cream in the relief of osteoarthritic pain of the knee: a double blind, placebo controlled, randomised interventional study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13351989

Enrollment

400

Registered

2016-02-09

Start date

2016-02-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee Musculoskeletal Diseases

Interventions

Patients who meet the radiographic inclusion criteria will be asked to initially evaluate the level of their pain in the knee on a Visual Analogue Scale (0 – 10). Based on the V.A.S scale result and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Osteoarthritis Stage (Kellgren & Lawrence Scale) 2 - 3 2. Patient’s Knee - Pain Self Evaluation (VAS 0 - 10) 4, 5, 6, 7

Exclusion criteria

Exclusion criteria: 1. Osteoarthritis Stage (Kellgren & Lawrence Scale) 0, 1, 4 2. Patient’s Knee- Pain Self Evaluation (VAS 0 - 10) 0 – 3 , 8 - 10 3. Use of analgesic or anti-inflammatory medications, topical or oral on the day of the study

Design outcomes

Primary

Measure	Time frame
Patient improvement on pain as evaluated by a Visual Analogue Scale (0-10) ten minutes after application of the cream.	—

Countries

Greece

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026