Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult patients (aged 18 years or older) admitted via the Emergency Department (ED) to either the general or neurosurgical ICU of one of the University College London Hospitals (UCLH) in North Central London between February 2010 and May 2012 2. Clinical diagnosis of acute ischaemic or intracerebral haemorrhagic stroke, confirmed by non-contrast cranial CT scan
Exclusion criteria
Exclusion criteria: 1. Patients with a subarachnoid or subdural bleeding 2. Patients with a known intra-cerebral or intracerebellar tumour 3. Patients who suffered an in-hospital stroke 4. Patients who were referred from another ICU for the same diagnosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality after ischaemic or intracerebral haemorrhagic stroke. The follow-up timepoints lie between 4 and 6 years (depending on when the patient suffered a critical stroke) or on the moment the patient died. | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional outcome, measured using the modified Rankin scale at hospital discharge and at one year follow-up check appointment and recorded by the patient’s primary treating physician. The original data using this ordinal scale will be dichotomised for analysis. Good functional outcome is defined as independent functional status (mRS 0-2) versus poor functional outcome, defined as dependent functional status or dead (mRS 3-6). Furthermore, transition in mRS will be taken into account, defined as improved functional status (mRS even or increased between discharge and after one year) versus declined functional status (mRS decreased between discharge and after one year). | — |
Countries
United Kingdom