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Prediction in patients who had a stroke and needed care at an intensive care unit concerning their changes of survival and the capacity to function in daily life after their illness

Clinical predictors of short-term and long-term survival and functional outcome of ICU-admitted stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN13328713
Enrollment
100
Registered
2017-03-18
Start date
2010-02-01
Completion date
Unknown
Last updated
2019-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Demographic and clinical data were obtained from the national, trust and hospital databases. Patients were selected if they were admitted to one of our four ICUs between February 2010 and May 2012 wit

Sponsors

University College London Hospital NHS Foundation Trust
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Adult patients (aged 18 years or older) admitted via the Emergency Department (ED) to either the general or neurosurgical ICU of one of the University College London Hospitals (UCLH) in North Central London between February 2010 and May 2012 2. Clinical diagnosis of acute ischaemic or intracerebral haemorrhagic stroke, confirmed by non-contrast cranial CT scan

Exclusion criteria

Exclusion criteria: 1. Patients with a subarachnoid or subdural bleeding 2. Patients with a known intra-cerebral or intracerebellar tumour 3. Patients who suffered an in-hospital stroke 4. Patients who were referred from another ICU for the same diagnosis

Design outcomes

Primary

MeasureTime frame
All-cause mortality after ischaemic or intracerebral haemorrhagic stroke. The follow-up timepoints lie between 4 and 6 years (depending on when the patient suffered a critical stroke) or on the moment the patient died.

Secondary

MeasureTime frame
Functional outcome, measured using the modified Rankin scale at hospital discharge and at one year follow-up check appointment and recorded by the patient’s primary treating physician. The original data using this ordinal scale will be dichotomised for analysis. Good functional outcome is defined as independent functional status (mRS 0-2) versus poor functional outcome, defined as dependent functional status or dead (mRS 3-6). Furthermore, transition in mRS will be taken into account, defined as improved functional status (mRS even or increased between discharge and after one year) versus declined functional status (mRS decreased between discharge and after one year).

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026