Depression Mental and Behavioural Disorders
Conditions
Interventions
The design of this study used a randomized controlled trial to prove the effectiveness of clinical hypnosis in improving subjective well-being and quality of life before and after the intervention. Du
Sponsors
Gadjah Mada University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 21 – 50 years old 2. Symptoms of depression 3. Willing to follow COVID-19 health procedures and all series of offline research activities as evidenced by signing informed consent 4. Do not have conditions that prevent them from following the course of therapy, do not have problems understanding instructions, comorbid with other physical and psychological illnesses that do not allow Clinical Hypnosis intervention, such as schizophrenia, attention disorders and so on 5. Not currently involved in other psychotherapy/research
Exclusion criteria
Exclusion criteria: 1. 20 years old and under or 51 years old and over 2. No symptoms of depression 3. Unwilling to follow COVID-19 health procedures and the entire series of offline research activities 4. Have conditions that prevent them from following the course of therapy, have problems capturing instructions, comorbid with other physical and psychological illnesses that do not allow clinical hypnosis intervention, such as schizophrenia, attention disorders and so on 5. Involved in psychotherapy/other research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Current primary outcome measure as of 10/02/2025: Subjective Well-Being 1. Subjective wellbeing measured using the Personal Well-being Index (PWI) consisting of seven mandatory items, including standard of living, life achievement, personal health, personal relationships, personal safety, social relationships, future security, and two additional items that have been adapted to the Indonesian culture at baseline and 14 days Quality of Life 2. Quality of Life (QoL) measured using the WHOQOL-BREF scale which measures the quality of life of individuals based on four domains, namely physical health, psychological, social relationships, and the environment at baseline and 14 days Positive and Negative Emotions 3. Positive and negative emotions measured using the Expanded Form of Positive and Negative Affects Schedule (PANAS-X), which contains 60 items with a Likert scale that specifically measures positive and negative emotions as well as other emotions at baseline, two hours (after therapy), and 14 days Depression 4. Depression of participants measured using the Patient Health Questionnaire (PHQ-9). The PHQ-9 scale has 9 items, with 4 answer choices using a Likert scale at baseline and 14 days _____ Previous primary outcome measure: Subjective Well-Being 1. Subjective wellbeing measured using the Personal Well-being Index (PWI) consisting of seven mandatory items, including standard of living, life achievement, personal health, personal relationships, personal safety, social relationships, future security, and two additional items that have been adapted to the Indonesian culture at baseline and 14 days Quality of Life 2. Quality of Life (QoL) measured using the WHOQOL-BREF scale which measures the quality of life of individuals based on four domains, namely physical health, psychological, social relationships, and the environment at baseline and 14 days Positive and Negative Feelings 3. Positive and negative feelings measured using the Expanded Form of Positive | — |
Secondary
| Measure | Time frame |
|---|---|
| Current secondary outcome measures as of 10/02/2025: Biofeedback 1. Physical condition measured using heart rate variability (HRV), and galvanic skin response (GSR) during the hypnosis process. HRV and GSR use a tool made by CV Amakusa Instrumentation Technology called GSR AIT - 06. Biomarkers 2. Salivary cortisol biomarkers and alpha-amylase levels in saliva measured using standard ELISA procedures in a laboratory at baseline and then 14 days _____ Previous secondary outcome measures: Biofeedback 1. Physical condition measured using electroencephalogram (EEG), heart rate variability (HRV), and galvanic skin response (GSR) during the hypnosis process. The specifications of the EEG tool used are Digital Brain Electric Activity Mapping, Contec™ brand, Model: KT88-3200. While HRV and GSR use a tool made by CV Amakusa Instrumentation Technology called GSR AIT - 06. Biomarkers 2. Salivary cortisol biomarkers and alpha-amylase levels in saliva measured using standard ELISA procedures in a laboratory at baseline and then 14 days | — |
Countries
Indonesia
Outcome results
None listed