Comparison of two analgesic combinations for reno-ureteral colic treatment

Analgesic efficacy of ketorolac/metamizole versus diclofenac/butylhyoscine for reno- ureteral colic management in a primary-care hospital emergency service

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13320231

Enrollment

Registered

2022-04-04

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-09-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reno-ureteral colic management Urological and Genital Diseases

Interventions

Participants will be randomized 1:1 to receive the intervention or the comparison treatment. This process will occur when the patient arrives at the Emergency service from the primary-care hospital an

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 60 years 2. Clinical signs and symptoms of reno-ureteral colic

Exclusion criteria

Exclusion criteria: 1. Hypersensitivity to any of the tested drug formulations 2. Patients with severe reno- ureteral colic (with fever and chronic pain) 3. Grade III and IV renal insufficiency 4. Patients will be excluded if they have any pre-existing treatment that might interact with the tested drug 5. Patients will be excluded if they possess pre-existing digestive tube bleeding

Design outcomes

Primary

Measure	Time frame
Pain is measured using a visual analogue scale (VAS) at baseline, 10, 20, and 45 min	—

Secondary

Measure	Time frame
The brief pain inventory (short form in Spanish) will be applied to assess the severity of pain and its impact on functioning at baseline	—

Countries

Mexico

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026