Obesity among children Nutritional, Metabolic, Endocrine
Conditions
Interventions
Current interventions, as of 17/06/2024:
The intervention will be provided in 4 phases: (1) preconception, (2) pregnancy, (3) infancy [0-2 years], and (4) early childhood [3-5 years]. Each phase has
70%) will be followed until age 5 years and assessed for the primary and secondary outcomes. Pregnancy, infancy (age 2 years), and parental outcomes will also be assessed. In addition, among the 4444
Sponsors
Canadian Institutes of Health Research
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Current inclusion criteria as of 17/06/2024: 1. Non-pregnant female 2. No child OR a child between 3-12 months postpartum 3. Planning a pregnancy in the next 3 years 4. Understands written English, 5. Resides in Canada ______ Previous inclusion criteria: 1. Non-pregnant female 2. No child OR one child between 3-12 months postpartum 3. Planning a pregnancy in the next 3 years 4. Understands written English, 5. Resides in Ontario or Alberta
Exclusion criteria
Exclusion criteria: Current exclusion criteria as of 17/06/2024: 1. Type 1 diabetes _____ Previous exclusion criteria: 1. Type 1 diabetes 2. Two or more children
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Child overweight and obesity rate (at age 5 years) measured as the proportion of children with BMI >85 percentile using the WHO growth reference ranges, by sex, at age 5 years. Height/length and weight will be measured using standardized instruments and procedures. | — |
Secondary
| Measure | Time frame |
|---|---|
| Child outcomes (all at age 5 years): 1.1 The reduction of the mean age and sex-adjusted BMI z-scores at age 5 as well as growth trajectories, as measured by BMI z scores from birth to age 5. BMI-z scores will be defined using the WHO growth standards, and reference ranges, as appropriate by age. Head circumference will be measured as part of the growth trajectory. 1.2 Cardiometabolic risk (CMR) will be measured as the sum of z-scores from waist circumference, systolic blood pressure, glucose, triglycerides, and (inverse) high-density lipoprotein (HDL). Individual measures will also be examined as continuous variables. Other measures including diastolic blood pressure, blood measures (total cholesterol, LDL, non-HDL, HbA1c, CRP, and insulin) will be collected. 1.3 Health Behaviours: 1.3.1 Dietary intake will be measured using the parent-reported Canadian adaptation of the automated self-administered 24-hour dietary assessment tool (ASA24-Canada). 1.3.2 Physical activity, screen time, and sleep will be measured using questions adapted from the Canadian Health Measures Survey and the 24-hour movement guidelines for children and youth. 1.4 Development and mental health: Cognitive development will be measured using the Wechsler Preschool and Primary Scale of Intelligence (WPPSI-IV) and executive function using the Neuro-PSYchological Assessment NEPSY-II administered by psychometrists. 1.5 Behavioural development will be measured using the Strengths and Difficulties Questionnaire and the Child Behavioural Questionnaire (CBQ). 1.6 Emotional development will be measured using the parent-reported, Age-specific Ages and Stages Questionnaire Socio-emotional Scale (ASQ-SE). 1.7 School readiness will be measured using the Early Development Instrument (EDI). 1.8 Health care utilization will be collected using provincial administrative data (e.g. ICES in Ontario). This will include measurement of routine child outpatient health visits, including adherence to vaccination sche | — |
Countries
Canada
Contacts
Public ContactAlvaro Ferreira
Outcome results
None listed