Peripheral arterial disease (PAD) Circulatory System Peripheral arterial disease (PAD)
Conditions
Interventions
GP Practices will identify eligible patients and send invite letters in the post. Once an invite is accepted, the GP Practice will match the PAD patient with a control (matched by age and sex) and sen
Sponsors
Newcastle upon Tyne Hospitals NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients: 1. Aged 45 years and over 2. Provision of informed consent 3. Diagnosed with PAD Controls: 1. Aged 45 years and over 2. Provision of informed consent 3. Not diagnosed with PAD
Exclusion criteria
Exclusion criteria: 1. Those under 45 years of age 2. Those unable to provide informed consent. 3. Individuals with renal failure receiving renal support therapy (ESRF) 4. Patients with tender or painful calves, ankles or feet who would be unable to tolerate ABPI measurements (ulcerated legs) 5. Toe/limb amputees (bilateral comparisons needed to make pulse and pressure-based assessments) 6. PPG measurement site (big toe pad, index finger pad, earlobe) having any visible damage to local skin area (skin needs to be intact) 7. Significant limb tremor 8. Patients unable to understand English sufficiently to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy of MPPG and ABPI with each compared with Duplex scan using values of sensitivity, specificity, and positive and negative predictive values. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcome measures. | — |
Countries
England, United Kingdom
Outcome results
None listed