Identifying molecules in the blood associated with long term healing problems in long bone fractures

Bioinformatic analysis and experimental identification of blood biomarkers for chronic nonunion

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13271153

Enrollment

100

Registered

2020-05-04

Start date

2018-08-01

Completion date

Unknown

Last updated

2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nonunion of open fractures of long bone Musculoskeletal Diseases

Interventions

Patients admitted to the Department of Orthopedics of Xuanwu Hospital between August 2018 and July 2019, are enrolled in this study. The group is categorized into the Healed and Nonunion groups, accor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients diagnosed with open fractures of long bone and defined nonunion

Exclusion criteria

Exclusion criteria: Does not meet inclusion criteria

Design outcomes

Primary

Measure	Time frame
Biomarkers verified by ELISA and qPCR methods from a blood sample taken at a single time point	—

Countries

China

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 18, 2026