Achilles tendinopathy Musculoskeletal Diseases Achilles tendinitis
Conditions
Interventions
Participants are randomly allocated to one of two groups:
Control group: Participants receive a placebo injection into the skin near the painful tendon
Intervention g
Sponsors
University of Warwick
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Provision of written informed consent 2. Aged 18 years or over 3. Pain at the mid-substance of the Achilles tendon for longer than 3 months 4. Ultrasound and/or MRI confirmation of tendinopathy
Exclusion criteria
Exclusion criteria: 1. Presence of systemic conditions (including: diabetes, rheumatoid arthritis, peripheral vascular disease) 2. Pregnant or actively trying to become pregnant, or breastfeeding at the time of randomisation 3. Have had prior Achilles tendon surgery or rupture on the index side 4. Previous major tendon or ankle injury or deformity to either lower leg 5. Have had a fracture of a long bone in either lower limb in the previous 6 months 6. Have any contraindication to receiving a platelet rich plasma injection (haemodynamic instability, platelet dysfunction syndrome, cancer, septicaemia, systemic use of anticoagulant, local infection at site of the procedure) 7. Are unable to adhere to trial procedures or complete questionnaires 8. Previous randomisation in the present trial Added 19/10/2016: 9. Previous PRP treatment into a tendon.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dysfunction of the Achilles tendon (pain, function and activity) is measured using the Victorian institute of sport assessment-Achilles (VISA-A) questionnaire at baseline, 3 months and 6 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Health related quality of life is measured using the EQ5D-5L questionnaire at baseline, 3 months and 6 months Added 19/10/2016: 2. Pain is measured using a visual analogue score (VAS) is assessed at baseline, 2 weeks, 3 and 6 months using a patient questionnaire 3. Complications are recorded at 2 weeks, 3 and 6 months using a patient questionnaire | — |
Countries
England, Scotland, United Kingdom, Wales
Contacts
Public ContactBethany Foster
Outcome results
None listed