Pharmacokinetics profile of magnesium after intravenous and intramuscular magnesium sulfate administration in Indonesian pregnant women with pre-eclampsia

Pharmacokinetics profile of magnesium after intravenous and intramuscular magnesium sulfate administration in Indonesian pregnant women with pre-eclampsia: a randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13244564

Enrollment

Registered

2015-08-31

Start date

2013-06-01

Completion date

Unknown

Last updated

2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-eclampsia Pregnancy and Childbirth

Interventions

A total 70 pregnant women with pre-eclampsia were involved in this study. Subjects were divided into two groups with 35 subjects in each group. The intravenous group received an IV loading dose of Mg

10 min

28 and 30 h. The serum Mg concentrations were determined using the atomic absorption spectrophotometer method. Pharmacokinetics parameters including peak serum concentration (Cmax), time to reach peak

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Single pregnancy 2. Pre-eclampsia 3. Willing to join the study

Exclusion criteria

Exclusion criteria: 1. Magnesium intoxication 2. Other pregnancy complications

Design outcomes

Primary

Measure	Time frame
Serum magnesium level	—

Secondary

Measure	Time frame
Pharmacokinetics profile of magnesium sulfate	—

Countries

Indonesia

Contacts

Public ContactLily Marliany Surjadi

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026