Neuroimaging research of brain aging in the elderly in the community

Neuroimaging study on the correlation between brain aging and cognitive-motor function in the middle-aged and elderly population

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13222678

Enrollment

3000

Registered

2024-02-28

Start date

2018-12-01

Completion date

Unknown

Last updated

2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain aging Nervous System Diseases

Interventions

We intend to utilize the most current Quantitative susceptibility mapping (QSM) data available to examine and evaluate the correlation between iron accumulation and neuropsychiatric disorders. Extensi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age from 40 to 80 years old 2. Right-handedness

Exclusion criteria

Exclusion criteria: 1. History of brain trauma, surgery, or tumors 2. Acute complications of type 2 diabetes 3. Severe hypertension 4. History of severe cerebrovascular, neurological, or mental diseases 5. Alcohol or drug abuse 6. MRI contraindications

Design outcomes

Primary

Measure	Time frame
Brain iron is measured using Quantitative susceptibility mapping (QSM) at baseline, 2 years and 5 years.	—

Secondary

Measure	Time frame
Brain iron measured using QSM at 2 years.	—

Countries

China

Contacts

Public ContactLingfei Guo

guolingfei@sdfmu.edu.cn+86 531-68776789

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026