Nutritional interventions for Parkinson's Disease Nervous System Diseases
Conditions
Interventions
The research will involve a comparison of:
Intervention 1: 8 weeks of consuming a Standard American Diet as defined by the USDA Food Pyramid
Intervention 2: 8 weeks of consuming a Standard American Di
Sponsors
Colorado Parkinson Foundation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Between the ages of 30-85 years 2. Live in the United States 3. Can speak, read and understand English 4. Diagnosis of PD (H-Y Stages I-IV) 5. BMI>18.5 kg/m² 6. Ability to understand and follow an LCHF/KD diet 7. Obtained permission to participate from their Primary Care Provider (PCP) or neurologist 8. Signed the informed consent and the HIPAA Release of Medical Information form
Exclusion criteria
Exclusion criteria: 1. Does not meet inclusion criteria 2. Persons with PD H-Y Stage V 3. Persons with unstable/uncontrolled type 2 diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured before and after each 8-week diet period: 1. Blood biomarkers measured using blood test: 1.1. Biomarkers HDL 1.2. HgA1C 1.3. Triglycerides 1.4. Fasting Insulin 1.5. hs-C-Reactive Protein 2. Biometrics 2.1. BMI (kg/m²) 2.2. Waist circumference (cm) 3. Parkinson's symptoms 3.1. Cognition using scores on the Parkinson’s Disease Cognitive Rating Scale 3.2. Sleep quality as measured by the Epworth Sleepiness Scale and the Parkinson’s Disease Sleep Scale 3.3. Fatigue scores measured by the Parkinson’s Disease Fatigue Scale 3.4. Scores on Part I of the United Parkinson’s Disease Rating Scale (UPDRS) 3.5.Scores on Part II of the United Parkisnon’s Disease Rating Scale (UPDRS) | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
United States of America
Outcome results
None listed