Octenidine gel plus a hydrogel dressing compared with a silver alginate dressing for venous leg ulcers: a randomized clinical trial

Clinical effectiveness of octenidine gel with hydrogel dressing compared with silver-containing calcium alginate dressing in venous leg ulcers: randomized trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13181127

Enrollment

Registered

2025-12-30

Start date

2024-06-01

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic venous leg ulcers (VLUs) Skin and Connective Tissue Diseases

Interventions

Randomisation was implemented using sequentially numbered, sealed opaque envelopes containing the group allocation. Envelopes were opened only after a participant had been enrolled/consented. Experim

Volkmann spoon debridement as required). A silver-containing calcium alginate dressing was applied. Dressings were replaced every 3 days for 4 weeks.

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis of venous leg ulcer (VLU); non-venous origin excluded by Doppler ultrasonography 2. Chronic wound treated unsuccessfully for >3 months 3. Wound area 20–60 cm² 4. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Allergy to octenidine or silver 2. No written informed consent

Countries

Poland

Contacts

Public ContactKinga;Marek Spyrka;Kucharzewski

;

ikingaxd@gmail.com;m.kucharzewski@ujd.edu.pl+48 (0)501193857;+48 (0)660469080

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026