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Mobilizing voices for science to promote trust in vaccination: the health ambassadors multi-site randomized controlled trial

A multi-site randomized controlled trial of a health ambassadors intervention to promote trust in vaccination among adults in four sub-Saharan African countries

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13151175
Enrollment
3072
Registered
2024-02-16
Start date
2024-02-25
Completion date
Unknown
Last updated
2024-07-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trust in vaccination among adults eligible for vaccination but who were not vaccinated for COVID-19 Infections and Infestations

Interventions

This study targets adults residing in catchment areas (clusters) of selected urban health facilities in Côte d'Ivoire, Malawi, Senegal, and Zimbabwe where vaccines, including those for COVID-19, Typho

Sponsors

Evidence in Governance and Politics at the University of California, Berkeley
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Eligible participants are adults (at least 18 years old) who live in households located within the catchment areas of health facilities where the Health Ambassadors will be based (the catchment area is a 1km circular buffer surrounding the health facility) and who meet all the following three conditions: 1. At least one adult member of the household has not been vaccinated against COVID-19 at the baseline survey. 2. The head of the household or their representative consents to carry out the survey at the baseline and endline survey. 3. The head of the household or their representative consents to be contacted again by the research team.

Exclusion criteria

Exclusion criteria: 1. Below 18 or above 80 years of age 2. Resides in a household in which all adults over 18 were vaccinated for COVID-19 3. Head of household or adult representing the household does not consent to interview or future visits from the research team

Design outcomes

Primary

MeasureTime frame
Vaccine trust measured using the Vaccine Trust Index (VTI) for COVID-19 and other targeted vaccines at baseline prior to any intervention and then at endline, which will occur within 1 month after the end of the six-week intervention implementation period.

Secondary

MeasureTime frame
Vaccine uptake measured for each vaccine and each household member using: 1. Household member’s verbal affirmation of receiving the vaccination (yes or no) 2. Whether the household member provided documentation of vaccination (e.g. their vaccination card) (yes or no) Measured at baseline prior to any intervention and then at endline, which will occur within 1 month after the end of the 6-week intervention implementation period.

Countries

Cote d'Ivoire, Malawi, Senegal, Zimbabwe

Contacts

Public ContactCyrus Samii
cds2083@nyu.edu+1 (0)9173016421

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026