Effect of throat exercises in lower jaw advancement to treat sleep apnea

Influence of oropharyngeal exercises in the adherence and efficacy of mandibular advancement device therapy in patients with moderate obstructive sleep apnea: a multicentre randomized clinical trial pilot study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13128082

Enrollment

Registered

2023-04-17

Start date

2023-05-03

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep apnea Nervous System Diseases Sleep apnoea

Interventions

A myofunctional and anatomical evaluation of the patient diagnosed with obstructive sleep apnea/hypopnea syndrome (OSAHS) will be conducted in the same week as the polysomnography is performed. During

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 75 years 2. Diagnosis of moderate OSAHS (AHI between 15-30) without having had previous experience of said condition and not undergoing treatment due to different circumstances 3. Not having undergone any previous treatment for OSAHS 4. Signed informed consent (IC) form

Exclusion criteria

Exclusion criteria: 1. Cognitive or neurological deficit 2. Inability to answer questionnaires 3. Severe alcoholism 4. Presence of craniofacial malformations 5. Active neoplastic disease 6. History of prior orofacial muscle rehabilitation therapy and any prior apnoea treatment which may modify the study results (surgery, MAD, continuous positive airway pressure [CPAP]) 7. Not having a smartphone 8. Temporomandibular joint dysfunction 9. Absence of dentition to wear a MAD

Design outcomes

Primary

Measure	Time frame
Apnea-hypopnea index (AHI) measured by polysomnography/polygraphy measured on the first day and after 3 months	—

Secondary

Measure	Time frame
Measured on the first day and after 3 months (except for sleep diary): 1. Oxygen desaturation index (ODI) measured by polygraphy/polysomnography 2. Minimal O2 desaturation (min sat o2) measured by polygraphy/polysomnography 3. Strength of the genioglossus muscle measured by Tongue Digital Spoon (TDS) and Iowa Oral Performance Instrument (IOPI) 4. Adherence to the use of MAD measured by sleep diary daily 5. Sleepiness measured with the Epworth sleepiness scale subjective scale 6. Subjective measure of snoring by partner using Visual Analogue Scale (VAS) 7. Quality of sleep measured with Pittsburgh questionnaires 8. Oropharynx dimensions measured with Friedman anatomical scales	—

Measure

Time frame

Measured on the first day and after 3 months (except for sleep diary): 1. Oxygen desaturation index (ODI) measured by polygraphy/polysomnography 2. Minimal O2 desaturation (min sat o2) measured by polygraphy/polysomnography 3. Strength of the genioglossus muscle measured by Tongue Digital Spoon (TDS) and Iowa Oral Performance Instrument (IOPI) 4. Adherence to the use of MAD measured by sleep diary daily 5. Sleepiness measured with the Epworth sleepiness scale subjective scale 6. Subjective measure of snoring by partner using Visual Analogue Scale (VAS) 7. Quality of sleep measured with Pittsburgh questionnaires 8. Oropharynx dimensions measured with Friedman anatomical scales

—

Countries

Spain

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Aug 25, 2026