Chemotherapy induced peripheral neuropathy Nervous System Diseases
Conditions
Interventions
Following informed consent and after assessment 1, children will be randomised into two groups: usual care versus screening programme (using sealedenvelope.com ensuring allocation concealment).
1. In
Sponsors
Alder Hey Children's NHS Foundation Trust
Eligibility
Sex/Gender
All
Age
4 Years to 17 Years
Inclusion criteria
Inclusion criteria: Newly diagnosed children, 4-<18 years at high risk of CIPN (this will encompass the following diagnoses: children with Acute Lymphoblastic Leukaemia (ALL), Wilms Tumour, Rhabdomyosarcoma, Low grade brain tumour on LGG 2 Protocol). These children are classed as high risk of CIPN as their treatment protocol includes weekly vincristine during their treatment schedule. High incidence of CIPN in these patient groups has been reported in the literature.
Exclusion criteria
Exclusion criteria: 1. Medically unstable or presence of co-morbidities affecting safety of screening/outcome measure assessments, or those with relapsed disease. 2. Under the age of 4 years due to inability to complete the chosen outcome measures
Countries
England, United Kingdom
Contacts
Public ContactHelen Hartley
Outcome results
None listed