Reduction of SARS CoV-2 viral load Infections and Infestations
Conditions
Interventions
This single-blind, nonrandomized controlled clinical trial comprised 45 patients who were divided into three intervention groups: 0.2% chlorhexidine gluconate (MINOSEP®) mouthwash group (n = 15)
1% povidone iodine (BETADINE®) mouthwash group (n = 15), and mineral water (AQUATM, DANONE-Indonesia) control group (n = 15). The mouthwash was repackaged in a 125 ml bottles. Each subject received tw
Sponsors
University of Indonesia
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. SARS-CoV-2-positive patients based on RT-PCR results over the past <3 days 2. An RT-PCR CT value of =30 3. Outpatients with mild or no symptoms 4. Aged 20 to 50 years
Exclusion criteria
Exclusion criteria: 1. Patients with comorbidities 2. History of allergy to povidone iodine mouthwash and chlorhexidine gluconate 3. Pregnant females 4. Those who were not willing to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The CT values were estimated from the RT-PCR results at initial diagnosis, and on days 3 and 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| Cycle Threshold value of RT-PCR on day 3 and 5 | — |
Countries
Indonesia
Contacts
Public ContactLilies Dwi Sulistyani
Outcome results
None listed