Unstable angina pectoris (UAP) after elective percutaneous coronary intervention (PCI) Circulatory System Unstable angina
Conditions
Interventions
The patients are divided according to preprocedural antiplatelet therapy into two groups, a ticagrelor group and a clopidogrel group after PCI. In the ticagrelor group, patients are first treated with
Sponsors
First People's Hospital of Taicang
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Elderly UAP patients admitted to the Department of Cardiology of Taicang Hospital affiliated to Suzhou University (Taicang First People's Hospital) from May 2018 to May 2020 2. Successfully underwent an elective PCI operation with no complications during the perioperative period 3. Patients informed and agreed to participate in the study before and after inclusion
Exclusion criteria
Exclusion criteria: 1. Fatal or persistent bleeding diseases in the past 3 months 2. Severe liver and kidney insufficiency 3. New York Heart Association (NYHA) class III-IV heart failure 4. Patients who could not tolerate antiplatelet drug therapy 5. Patients who did not comply with the treatment regimen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatal bleeding events and MACCE: major bleeding defined as Bleeding Academic Research Consortium (BARC) type 3 to 5 bleeding, MACCE defined as an endpoint that could include cardiac death, non-fatal myocardial infarction, stroke, and target lesion revascularization (TLR) at 1 year after PCI | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of bleeding defined as BARC = grade 2 during 1 year after PCI | — |
Countries
China
Outcome results
None listed