Yoga-based mindfulness intervention for older adults with mild cognitive impairment

The impact of a yoga-based mindfulness intervention versus psycho-educational session for older adults with mild cognitive impairment: a randomized control trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13063260

Enrollment

Registered

2022-04-28

Start date

2021-09-13

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive and physical functions and mental health outcomes of older adults with mild cognitive impairment (MCI) Mental and Behavioural Disorders

Interventions

Participants within the outpatient clinic at Clinical Hospital-Universidad de Chile will be allocated to the intervention or the comparator with a 1:1 ratio based on random computer-generated numbers,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 60 years and above 2. People who have MCI diagnosed by three criteria: 2.1. By a neurologist and/or psychiatrist, and/or geriatrician, and/or the neuropsychologist. through evaluation by saying that they had memory problems confirmed by an informant (in case if they have a formal or informal caregiver or simply, their partner), (but without problems in their activities of daily living) 2.2. Score < 21 at the Montreal Cognitive Assessment (MoCA <21) 2.3. Without dementia according to the criteria of the Clinical Dementia Rating Scale (CDR) a score of 0.5

Exclusion criteria

Exclusion criteria: 1. People who did yoga and/or mindfulness within the last 6 months 2. The presence of a psychiatric clinical diagnosis; or neurological/cerebrovascular condition. 3. Presence of a disabling physical illness or/and presence of a disability that limits and/or impede communication such as major impairments in eyesight, and/or hearing or upper limb motor movements; and/or other health problem that would interfere with regular yoga and mindfulness practice

Design outcomes

Primary

Measure	Time frame
Cognitive function assessed using a Spanish version of Montreal Cognitive Assessment (MoCAS1- 2) via live video call at baseline and post-intervention, 3 and 6 months follow up.	—

Secondary

Measure	Time frame
Assessed using the telephone-based survey before random assignment (pre-test), the week following the last session of the intervention (post-test), and then at 3- and 6-months follow-up: 1. Physical function assessed using: 1.1. The Barthel Index (BI) to measure performance in activities of daily living (ADL) 1.2. The Lawton Instrumental Activities of Daily Living Scale (IADL) to assess the independent living skills of an individual and measures functional ability as well as declines and improvements over time 2. Psychological well-being assessed using the Pemberton happiness index 3. Anxiety assessed using the Geriatric Anxiety Inventory (GAI) 4. Depression assessed using the Geriatric Depression Scale (GDS-5)	—

Measure

Time frame

Assessed using the telephone-based survey before random assignment (pre-test), the week following the last session of the intervention (post-test), and then at 3- and 6-months follow-up: 1. Physical function assessed using: 1.1. The Barthel Index (BI) to measure performance in activities of daily living (ADL) 1.2. The Lawton Instrumental Activities of Daily Living Scale (IADL) to assess the independent living skills of an individual and measures functional ability as well as declines and improvements over time 2. Psychological well-being assessed using the Pemberton happiness index 3. Anxiety assessed using the Geriatric Anxiety Inventory (GAI) 4. Depression assessed using the Geriatric Depression Scale (GDS-5)

—

Countries

Chile

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026