Periodontial disease is a leucocyte-mediated inflammatory disease characterised by inflammation of the supporting tissues of the teeth induced by micro-organisms that stimulate the host immune and inflammatory responses. Oral Health Periodontial disease
Conditions
Interventions
Gingival crevicular fluid samples will be obtained from the orifice of the gingival pocket, using commercially available periopaper strips for the assessment of:
1. Plaque index
Sponsors
Ondokuz Mayis University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Smokers (= 5 years of duration and = 15 cigarettes per day) 2. Non-smokers (never smoked) 3. Age = 18 years old 4. = 16 teeth
Exclusion criteria
Exclusion criteria: 1. History of cancer 2. History of rheumatoid arthritis 3. History of diabetes mellitus 4. History of cardiovascular diseases 5. Compromised immune system 6. Pregnancy 7. Menopause 8. Lactating 9. Ongoing drug therapy that may affect the clinical features of periodontitis 10. Systemic antimicrobials during the 6 weeks preceding the baseline examination 11. Any dental treatment during the past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Silness and Loe plaque index 2. Loe and Silness gingival index 3. Probing pocket depth 4. Clinical attachment level 5. Bleeding on probing Clinical measurements will be performed on six sites per tooth (mesio-buccal, mid-buccal, disto-buccal, mesio-lingual, mid-lingua and, disto-lingual) using a Williams periodontal probe calibrated in millimetres on the patient's first visit to have periodontal treatment. | — |
Countries
Turkey
Outcome results
None listed