Pulmonary rehabilitation in COPD and interstitial lung diseases

The effectiveness of pulmonary rehabilitation in COPD and interstitial lung diseases

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN13019180

Enrollment

500

Registered

2018-01-16

Start date

2017-11-18

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD, interstitial lung diseases with or without pulmonary hypertension Respiratory

Interventions

This study tests the effectiveness of pulmonary rehabilitation on chest kinematics, lung mechanics, lung function, metabolism, peripheral and respiratory muscle function, exercise physiology and syste

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with COPD or interstitial lung disease 2. Age between 30 and 80 years 3. Able to perform respiratory training and endurance training 4. Able to understand the meaning of the program 5. Without significant psychological disease, which has influence the outcome of the rehabilitation

Exclusion criteria

Exclusion criteria: 1. Not able to perform the pulmonary rehabilitation program because of joint disease 1. Not able to perform the pulmonary rehabilitation program because of psychological disorder

Design outcomes

Primary

Measure	Time frame
1. Lung function is measured using spirometry at end of rehabilitation and at 6 and 12 months 2. Oxygen uptake is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at 6 and 12 months 3. Metabolism at the end of the rehabilitation is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at 6 and 12 months 4. Systemic inflammation is measured by routine laboratory methods for hsCRP, ELISA for cytokines, sputum and plasma concentration with HPLC at the end of rehabilitation, 6 and 12 months 5. Oxidative stress is measured by enzyme immunoassay techniques at the end of rehabilitation, 6 and 12 months	—

Measure

Time frame

1. Lung function is measured using spirometry at end of rehabilitation and at 6 and 12 months 2. Oxygen uptake is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at 6 and 12 months 3. Metabolism at the end of the rehabilitation is measured using the cardiopulmonary exercise test at the end of the rehabilitation and at 6 and 12 months 4. Systemic inflammation is measured by routine laboratory methods for hsCRP, ELISA for cytokines, sputum and plasma concentration with HPLC at the end of rehabilitation, 6 and 12 months 5. Oxidative stress is measured by enzyme immunoassay techniques at the end of rehabilitation, 6 and 12 months

—

Secondary

Measure	Time frame
1. Chest kinematics is measured using thoracic circumference at the end of the rehabilitation and at 6 and 12 months 2. Lung mechanics is measured using lung function at the end of the rehabilitation and at 6 and 12 months 3. Peripheral and respiratory muscle function is measured using grip strength and peripheral muscle force measurement at the end of the rehabilitation and at 6 and 12 months 4. Quality of life is measured using CAT marker and mMRC at the end of the rehabilitation and at 6 and 12 months	—

Measure

Time frame

1. Chest kinematics is measured using thoracic circumference at the end of the rehabilitation and at 6 and 12 months 2. Lung mechanics is measured using lung function at the end of the rehabilitation and at 6 and 12 months 3. Peripheral and respiratory muscle function is measured using grip strength and peripheral muscle force measurement at the end of the rehabilitation and at 6 and 12 months 4. Quality of life is measured using CAT marker and mMRC at the end of the rehabilitation and at 6 and 12 months

—

Countries

Hungary

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 11, 2026