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Understanding the hydration potential of commonly consumed drinks

Development of an hydration index: a randomized trial to assess the potential of different beverages to affect hydration status in adult males

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN13014105
Enrollment
72
Registered
2015-03-23
Start date
2014-02-21
Completion date
Unknown
Last updated
2016-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hydration status monitoring Not Applicable

Interventions

After baseline samples were collected, each participant consumed 1L of fluid over a 30-minute period (4 x 250 ml delivered at 7.5-min intervals) and hydration status was monitored at hourly intervals
Tesco, Hertfordshire, UK) or skimmed milk (0.1% fat
Tesco, Hertfordshire, UK). We obtained n=72 observations for water, and n=17 observations for each of the other test drinks.

Sponsors

University of Stirling (UK)
Lead Sponsor
Bangor University (UK)
Collaborator
Loughborough University (UK)
Collaborator

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Healthy male volunteers 2. Aged 18-35 3. BMI 18-27 kg/m2 4. No known cardiovascular, renal or metabolic disease 5. Moderately active 6. Moderate alcohol use

Exclusion criteria

Exclusion criteria: 1. Overweight or obese (BMI >27 kg/m2) 2. Competitive athletes during competition season 3. Current or former cardiovascular, renal or metabolic disease 4. Habitual consumption of alcohol (>21 units/week) or regular (>1/week) high (10 units) intake 5. History of psychiatric illness 6. Actively seeking to gain or lose weight 7. Currently taking prescribed medication

Design outcomes

Primary

MeasureTime frame
1. Net fluid balance over each hour for 4 hours (fluid ingested minus cumulative urine output) 2. Hydration Index at each hour over 4 hours (net fluid balance comparison to water as a control)

Secondary

MeasureTime frame
1. Urine and serum osmolality at baseline and at each hour following fluid ingestion for 4 hours (freezing point depression method within 48 hours of sample collection) 2. Sodium and potassium net balance assessed immediately post-drinking and each hour following fluid ingestion for 4 hours (flame photometry method within 5 days of sample collection)

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 14, 2026