Stromal vascular fraction cells for the treatment of critical limb ischemia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN13001382

Enrollment

Registered

2017-04-26

Start date

2015-02-01

Completion date

Unknown

Last updated

2020-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical limb ischemia Circulatory System Critical limb ischemia

Interventions

All participants undergo lipoaspiration in the hospital by plastic surgeon. This involves up to 200ml of lipoaspirate being collected so that stem cells can be isolated in the GMP qualified laboratory

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Smokers 2. Diabetic feet 3. Poor vascularisation of the limb 4. Prescribed amputation 5. Aged 18 years and over

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Age below 21

Design outcomes

Primary

Measure	Time frame
Pain is measured using the visual analogue scale (VAS) at baseline, 24, 48 and 72 hours post multiple injections.	—

Secondary

Measure	Time frame
1. Neovascularisation process is measured using angiography at baseline, 2 weeks, 2, 6, 12 and 24 months 2. Claudication index is assessed using a functional distance measurement test at baseline, 2 weeks, 2, 6, 12 and 24 months respectively	—

Countries

Lithuania

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Mar 9, 2026