Prevention of progression in cervical intraepithelial lesions in patients with HPV Infections and Infestations
Conditions
Interventions
A randomized pilot study was conducted between 2018 and 2019 to evaluate the effect of multivitamin supplementation in women with LSIL and HPV. Ethical approval was obtained from the Ethics Committee
Sponsors
Universidad Autónoma de Ciudad Juárez
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Women diagnosed with low-grade cervical intraepithelial lesions (LSIL) confirmed by colposcopy and histopathological biopsy 2. Age =20 years 3. Positive for human papillomavirus (HPV) infection
Exclusion criteria
Exclusion criteria: 1.Patients with High-Grade Squamous Intraepithelial Lesions (HSIL) , Cervical Cancer, and condylomas 2.Pregnant patients 3. Those who only attended at the beginning and did not return 4. HPV-negative patients at baseline 5. Those who did not sign the informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regression, persistence, or progression assessed by colposcopic evaluation before and after six months of supplementation measured using patient records | — |
Secondary
| Measure | Time frame |
|---|---|
| Viral load measured by endpoint PCR and optical densitometry before and after six months of supplementation | — |
Countries
Mexico
Contacts
Public ContactAna Lidia Arellano-Ortiz
Outcome results
None listed