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How gum treatment may help improve blood sugar control in people with type 2 diabetes

Effect of non-surgical periodontal therapy on diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12954826
Enrollment
100
Registered
2026-01-20
Start date
2024-06-12
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Whether non-surgical periodontal therapy can improve glycemic control and systemic inflammation in patients with type 2 diabetes mellitus by reducing periodontal inflammation. Nutritional, Metabolic, Endocrine

Interventions

The intervention consists of non-surgical periodontal therapy, including full-mouth scaling and root planing performed using manual and/or ultrasonic instruments, combined with standardized oral hygie

Sponsors

University of Medicine Tirana
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-70 years 2. T2DM diagnosis 3. HbA1c = 7% 4. More than 10 teeth present 5. Periodontitis present = 4 teeth, at least one site PD = 5mm 6. BOP = 10%

Exclusion criteria

Exclusion criteria: 1. Professional periodontal treatment within the last 6 months 2. Systemic antibiotics within the last 3 months 3. Systemic diseases that may affect the response or direct periodontal damage 4. Current or previous oral mucosal diseases (e.g. Pemphigus, Lichen planus, Behcet's syndrome, etc.) 5. Pregnancy or breastfeeding 6. Inability to follow up at 0/3/6 months 7. Refusal to consent participation

Countries

Albania

Contacts

Public ContactBesian Abazi
abazi.besian@gmail.com+355 674171777

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 7, 2026