Perioperative Medicine Surgery Anaesthesia, Perioperative Medicine and Pain Management
Conditions
Interventions
Participants are recruited pre operatively either at pre-operative clinic or at the anaesthetic visit immediately prior to surgery and are asked to complete the Rey Auditory Verbal Learning Test (RAVL
Sponsors
University Hospital Of South Manchester NHS Foundation Trust
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Participant is willing and able to give informed consent for participation in the study 2. Male or Female, aged 18 years or above at point of consent 3. Participant is due to undergo elective or urgent cardiac surgery 4. Able (in the Investigators opinion) and willing to comply with all study requirements
Exclusion criteria
Exclusion criteria: 1. Patients undergoing emergency cardiac surgery 2. Participant undergoing transplantation surgery or Mechanical Circulatory Support Implantation surgery. 3. Participants undergoing aortic surgery with Deep Hypothermic Circulatory Arrest 4. Patients already unconscious, sedated or anaesthetised before surgery 5. Patients unable to provide informed consent 6. Significant alcohol intake preoperatively (> 50 units/week) 7. Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the primary outcome measure, delirium rate, is measured using the Rey Auditory Verbal Learning Test both immediately prior to surgery and at 6-12 weeks (+/-7 days) following extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Post-operative CerebroVascular Accident CVA confirmed by CT scan as per standard care at followup within two days of surgery. 2. Post-operative renal dysfunction measured using RIFLE Scoring 3. ITU length of stay measured using hospital records at discharge 4. Post-operative Cognitive Dysfunction measured using RAVLT at 6-12week follow up | — |
Countries
United Kingdom
Outcome results
None listed