Lung cancer Cancer
Conditions
Interventions
Participants will have two study visits - the first one will be at the same time as their lung health check/ clinic appointment, or on a different day if this is more convenient for them and the secon
Sponsors
University of Manchester
Eligibility
Sex/Gender
All
Age
40 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. ALL 1.1. Self-reported current cigarette smoker 1.2. Carbon Monoxide (CO) reading >=5 ppb 1.3. Intends to quit smoking / undertake a smoking quit attempt within 3 months 1.4. No prior history of cancer 1.5. Able to provide informed consent 2. Lung Health Check attendees 2.1. Aged >=55 years 2.2. PLCOM2012 score >=1.51% (or eligible for screening if alternative risk model is used) 3. MFT-CURE attendees 3.1. Aged >=40 years
Exclusion criteria
Exclusion criteria: 1. All 1.1. Never or former smoker (has not smoked within the last 2 weeks) 1.2. Carbon Monoxide (CO) reading <5 ppb 1.3. Prior history of cancer 2. Lung Health Check attendees 2.1. Aged <55 years 2.2. Decline or unable to undertake LDCT screening 3. MFT-CURE attendees 3.1. Aged <40 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Molecular signals measured by molecular signature as observed in mouth and nose samples, at baseline and follow-up (9 – 12 months) | — |
Secondary
| Measure | Time frame |
|---|---|
| There are no secondary outcome measures | — |
Countries
England, United Kingdom
Outcome results
None listed