Referred to cardiac rehabilitation programmes post- angioplasty, coronary artery bypass grafting or prescribed medical management only as treatment for an acute coronary syndrome Circulatory System Acute ischaemic heart disease, unspecified
Conditions
Interventions
The acute study compared cardiovascular measures pre and post the first bout of yoga in participants randomised to the yoga arm only, the chronic study compared cardiovascular measures at 3 months bet
Sponsors
Imperial College London
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Referred to cardiac rehabilitation programmes post- angioplasty, coronary artery bypass grafting or prescribed medical management only as treatment for an acute coronary syndrome 2. Age 35-80
Exclusion criteria
Exclusion criteria: 1. Co-morbid disease or mobility limitations that would preclude participation in cardiac rehabilitation, yoga or study investigations 2. Unable to understand either English or Punjabi
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acute study: Brachial blood pressure recovery after the Dundee 3-minute step test, measured on the day of the first yoga session, before and after the first yoga session. For each set of readings, blood pressure and heart rate are measured using an OMRON oscillometric device before the step test, immediately after the step test and then at 3 minutes after the step test Chronic study: 1. Left ventricular diastolic function, measured using echocardiography at baseline and at three months follow-up. The ratio of early filling to early myocardial velocity (E/e’) is used to estimate left ventricular diastolic function 2. 24 hour ambulatory blood pressure, measured using a Mobilograph oscillometric cuff-based device at baseline and at three months follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| Acute study: 1. Salivary cortisol as a measure of the hypothalamic-pituitary axis, measured from consecutive saliva samples taken by the participant using the Salivette self collection system on 5 occasions on the day of the first yoga session 2. Salivary alpha amylase as a measure of autonomic function measured from consecutive saliva samples taken by the participant using the Salivette system on 5 occasions on the day of the first yoga session Chronic study: 1. Brachial blood pressure recovery after the Dundee 3-minute step test, measured at baseline and at three months follow-up. For each set of readings, blood pressure and heart rate are measured using an OMRON oscillometric device before the step test, immediately after the step test and then at 3 minutes after the step test 2. Resting blood pressure, measured using a Pulsecor (applanation tonometry) device at baseline and three months follow-up 3. Central blood pressure, measured using a Pulsecor device at baseline and three months follow-up 4. Pulse wave velocity, measured using a Vicorder oscillometric device at baseline and three months follow-up 5. Salivary cortisol as a measure of the hypothalamic-pituitary axis, measured from consecutive saliva samples taken by the participant using the Salivette system on 5 occasions on one day at baseline and on one day at three months follow-up 6. Glucose, total and LDL cholesterol, measured from venous blood samples at baseline and three months follow-up 7. Anthropometric measures to assess obesity at baseline and three months follow-up 8. Body fat percent, measured using a Tanita bioimpedance device at baseline and three months follow-up 9. Autonomic function: heart rate variability and baroreflex sensitivity measured at baseline and three months follow-up. Beat to beat arte | — |
Countries
England, United Kingdom
Contacts
Public ContactTherese Tillin
Outcome results
None listed