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To determine whether changes in pulse wave velocity predict hypotension during dialysis

Study to determine whether changes in pulse wave velocity are associated with changes in blood pressure in haemodialysis patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ISRCTN
Registry ID
ISRCTN12870218
Enrollment
100
Registered
2013-11-01
Start date
2013-01-01
Completion date
Unknown
Last updated
2017-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Haemodialysis Circulatory System Haemodialysis

Interventions

All participants have a blood pressure cuff placed around their non fistula arm. Blood pressure measurements are taken three times spaced three minutes apart, during which time pulse wave velocity mea

Sponsors

Royal Free Hospital (UK)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with chronic kidney disease treated by haemodialysis 2. Patients who are able to provide valid consent 3. Patients who can have their blood pressure measured using an arm blood pressure cuff

Exclusion criteria

Exclusion criteria: 1. Patients who do not fulfil the inclusion criteria 2. Patients who cannot provide valid informed consent 3. Patients who cannot have their blood pressure measured using an upper arm blood pressure cuff 4. Those with atrial fibrillation and other cardiac arrhythmias

Design outcomes

Primary

MeasureTime frame
Blood pressure and pulse wave velocity are measured using a blood pressure cuff. Blood pressure will be measured at the start of a dialysis session, then at 20 minutes, one hour and then hourly during the dialysis session. Changes in pulse wave velocity and heartbeat variation will be reviewed to determine whether these are related to changes in blood pressure during the dialysis session.

Secondary

MeasureTime frame
Derived variables from pulse wave velocity.

Countries

United Kingdom

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026