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Repetitive transcranial magnetic stimulation of the primary motor cortex improves movement performance by regulating neural oscillations

TMPRNO: rTMS of M1 improves movement performance by regulating neural oscillations

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12867198
Enrollment
25
Registered
2024-10-11
Start date
2022-04-05
Completion date
Unknown
Last updated
2024-10-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Improve motor cortical excitability and balance dysfunction to provide practical guidance for the task-related brain state (TCBS) treatment of movement-related diseases, such as stroke Nervous System Diseases

Interventions

Electroencephalography (EEG) signals were collected from 32 Ag-AgCl scalp electrodes located according to the International 10-10 system using a BrainAmp system (Brain Products, Gilching, Germany). Th

Sponsors

Yanshan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Criteria specified in the TMS safety guidelines 2. Right-handed hand 3. Age range: 20-75 years old 4. No metal implants on the head 5. Healthy, No neurological or psychiatric disorders 6. No severe visceral diseases such as liver, lung, heart, kidney, etc 7. Voluntarily participate and sign an informed consent form 8. No severe motor function and able to complete exercise tests 9. Not receiving any drug treatment

Exclusion criteria

Exclusion criteria: 1. A history of neurological or psychiatric disorders 2. Receiving any drug treatment 3. Unwilling to have TMS 4. Unwilling to record EEG 5. Contraindications to magnetic stimulation

Design outcomes

Primary

MeasureTime frame
The following primary outcome measures were assessed using electromyography before intervention (TASK), 5 min after intervention (TASK5), and 20 min after intervention (TASK 20): 1. Reaction time, characterized between the ‘0’ cue and feedback 2. Movement performance, defined as the percentage of the sum of OK and GOOD among total trials

Secondary

MeasureTime frame
Motor cortical excitability measured using electroencephalography (EEG) during a resting state with eye open (pre-REST), 0 min after intervention (POST0) and with a resting state 25 min after intervention (post-REST)

Countries

China

Contacts

Public ContactLingdi fu
lingdifu123@126.com+86 15022071790

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026