Skip to content

Life Review Therapy for Holocaust Survivors: A study to evaluate the efficacy of a treatment

Life Review Therapy for Holocaust Survivors (LRT-HS): A randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12823306
Enrollment
50
Registered
2018-04-26
Start date
2017-12-01
Completion date
Unknown
Last updated
2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-traumatic stress disorder (PTSD), depression, anxiety disorder, prolonged grief. At least one of these conditions must be present at study intake, either at syndromal (DSM-5 diagnoses) or subsyndromal level. Mental and Behavioural Disorders

Interventions

Participants’ symptoms of PTSD, depression, anxiety, and grief are assessed and they are randomised at a 1:1 ratio to either: 1. Life-review therapy, in addition to social club (LRT) 2. Supportive con
Structured life review
Narrative exposition
Examining stuck points
Recapturing life
Closing of therapy. 20 sessions. In addition to attending the social club at Amcha. Control: "Social club" at Amcha centers
is a meeting place which answers the need to relate to others. It provides activities like films, lectures, courses in art, music, memory improvement, gymnastics, languages (English, Yiddish), visits

Sponsors

University of Siegen
Lead Sponsor
Herzog Hospital
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Being a Holocaust survivor, i.e., born 1945 or earlier in Europe and having experienced persecution, concentration camp, witnessing torture or death, or having to survive in hiding and/or other traumatic events by the Nazi regime during World War II. 2. Diagnosis of one or more of the following conditions: PTSD, complex PTSD, depressive disorder (Major, minor depression), anxiety disorder, prolonged grief disorder. Patients with a subsyndromal form of the mentioned disorders can also be admitted to the study. 3. Participants do not receive any psychotherapy treatment during the time of the study (except for LRT in the intervention condition). 4. Participants must have been informed about the study and must have given written informed consent. This includes that he/she is willing to be randomized to one of the study conditions.

Exclusion criteria

Exclusion criteria: 1. Probable dementia (MMSE < 26), 2. Acute psychotic disorder 3. Acute suicidality

Design outcomes

Primary

MeasureTime frame
Primary endpoints are PTSD and depressive symptoms, assessed at baseline, end of treatment, follow-up at 6 months: 1. PTSD symptoms assessed using PTSD Checklist for DSM-5 (PCL-5) 2. Depressive symptoms assessed using Patient Health Questionnaire (PHQ-9) and Geriatric Depression Scale (GDS)

Secondary

MeasureTime frame
Secondary outcome measures are assessed at baseline, end of treatment, follow-up at 6 months: 1. Other symptom measures - Complex PTSD symptoms: The complex PTSD part of the ICD-11 Trauma Questionnaire - Anxiety symptoms: The Depression Anxiety Stress Scale-21 (DASS-21) - Grief symptoms: The ICD-11 Symptom-Diagnostic Test for Prolonged Grief Disorder (PG-ICD-11) 2. Process measures - Dysfunctional thoughts: The Posttraumatic Cognitions Inventory (PTCI) - Reminiscence style: The Reminiscence Functions Scale (RFS) - Positive well-being: The Life Satisfaction Index (LSI) - Posttraumatic growth: The Posttraumatic Growth Inventory (PTGI) 3.Furthermore, sociodemographic characteristics (age, gender, educational level) and cognitive status (Mini Mental Status Examination, MMSE) are assessed at baseline.

Countries

Israel

Contacts

Public ContactElisheva van der Hal-van Raalte

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 27, 2026