The association of genetic variants and outcome of in vitro fertilization cycles

The research of gene polymorphisms of hormonal signals genes in women entering in vitro fertilization program

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ISRCTN

Registry ID

ISRCTN12768989

Enrollment

2000

Registered

2016-01-07

Start date

2013-12-23

Completion date

Unknown

Last updated

2025-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

In vitro fertilization (IVF) Pregnancy and Childbirth In vitro fertilization (IVF)

Interventions

All participating patients received controlled ovarian hyperstimulation protocols and oocyte retrieval procedures to get a number of oocytes. These oocytes were processed with in vitro fertilization/i

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Age 20 to 45 years old 2. Infertile patients who need IVF treatment 3. Qualified for IVF treatment

Exclusion criteria

Exclusion criteria: 1. Part of the oocyte donation program 2. Part of the sperm donation program

Design outcomes

Primary

Measure	Time frame
Oocyte number, measured using microscopy observation at the time of oocyte retrieval	—

Secondary

Measure	Time frame
1. Embryo quality is measured using microscopy observation for the number of blastomere, fragmentation degree at day 3 or day 5 after oocyte retrieval 2. Pregnancy rate is measured using serum beta-HCG test and ultrasound examination at 18 days and 32 days after oocyte retrieval, respectively 3. Implantation rate is measured using the total sac numbers divided by total transfer embryo number at the time of ultrasound examination	—

Measure

Time frame

1. Embryo quality is measured using microscopy observation for the number of blastomere, fragmentation degree at day 3 or day 5 after oocyte retrieval 2. Pregnancy rate is measured using serum beta-HCG test and ultrasound examination at 18 days and 32 days after oocyte retrieval, respectively 3. Implantation rate is measured using the total sac numbers divided by total transfer embryo number at the time of ultrasound examination

—

Countries

Taiwan

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026