Prevention of malnutrition in 6-24 month-old children Nutritional, Metabolic, Endocrine
Conditions
Interventions
This is a cluster randomized, community-based controlled trial, which tests the effectiveness of a diversified complementary food intervention on diet quality and nutritional status of young children.
Sponsors
Kenyatta University
Eligibility
Sex/Gender
All
Age
6 Months to 18 Months
Inclusion criteria
Inclusion criteria: 1. Aged 6-18 months 2. Living within the catchment area 3. Lived in the study area for 6 months before the trial 4. Caregiver able and willing to participate in both clinic and home visits 5. Written informed consent given by parent/caregiver
Exclusion criteria
Exclusion criteria: 1. Severe acute malnutrition; measured as mid-upper arm circumference (MUAC) < 115 mm or weight-for-length z-score (WLZ) < -3 or bilateral pitting oedema 2. Known critical or chronic condition which may affect the nutrition status of the child 3. Participation in another study or program which impacts this study or previously enrolled in this study 4. Family plans to move away from the catchment area in the next 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of food groups consumed measured using the Minimum Dietary Diversity (MDD) questionnaire at baseline, 1, 2, 3, 4, 5, and 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Proportion meeting minimum dietary diversity score measured using the MDD questionnaire at baseline, 1, 2, 3, 4, 5, and 6 months 2. Proportion meeting minimum acceptable diet measured using the MDD questionnaire + minimum meal/milk frequency at baseline, 1, 2, 3, 4, 5, and 6 months 3. Weight gain (g) measured using a standard paediatric weighing scale to the nearest 100 g at baseline, 1, 2, 3, 4, 5, and 6 months 4. Mid-upper arm circumference (cm) (MUAC) measured using a non-elastic MUAC tape at baseline, 1, 2, 3, 4, 5, and 6 months 5. Length (cm) measured using a Seca length board to the nearest 0.1 cm at baseline, 1, 2, 3, 4, 5, and 6 months 6. Length-for-age z-score calculated using AnthroPlus software at baseline, 1, 2, 3, 4, 5, and 6 months 7. Weight-for-length z-score calculated using AnthroPlus software at baseline, 1, 2, 3, 4, 5, and 6 months 8. Weight-for-age z-score calculated using AnthroPlus software at baseline, 1, 2, 3, 4, 5, and 6 months 9. Body composition (fat-free mass (kg), fat mass (kg), fat-free mass index (kg/cm2), fat mass index (kg/cm2)) measured using bioelectrical impedance analysis at baseline and 6 months 10. Haemoglobin (g/L) measured using Hemocue at baseline and 6 months 11. Inflammation-corrected serum ferritin (ug/L) measured using high throughput ELISA at baseline and 6 months 12. Serum soluble transferrin receptor (mg/L) measured using high throughput ELISA at baseline and 6 months 13. Serum C-reactive protein (mg/L) measured using high throughput ELISA at baseline and 6 months 14. Serum alpha-1-acid glycoprotein (g/L) measured using high throughput ELISA at baseline and 6 months 15. Inflammation-corrected retinol-binding protein measured using high throughput ELISA at baseline and 6 months 16. Insulin-like growth factor-1 measured using Cobas instrument at baseline and 6 months 17. Adverse events measured using study records at 1, 2, 3, 4, 5, and 6 months 18. Care-giver reported morbidity measured using caregiver recall (the l | — |
Countries
Kenya
Contacts
Public ContactJuliana Kiio
Outcome results
None listed