Efficacy of mouth-rinses in reducing SARS CoV-2 viral load in the saliva of COVID-19 positive patients in Indonesia

Efficacy of commercial mouth-rinses on SARS-CoV-2 viral load in saliva: a randomized control trial in Indonesia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12721265

Enrollment

Registered

2021-04-30

Start date

2021-05-10

Completion date

Unknown

Last updated

2021-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reducing the transmission of SARS CoV-2 virus in saliva of COVID-19 patients in Indonesia. Infections and Infestations COVID-19 (SARS-CoV-2 infection)

Interventions

The enrolled patients are randomized using Robust Randomization App (RRApp) using a block randomization technique and are allocated to four groups accordingly— PI, NaClO2, CPC and water control group.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Laboratory-confirmed COVID-19 positive patients

Exclusion criteria

Exclusion criteria: 1. History of allergy to PI, NaClO2, CPC and its relevant excipients 2. All forms of thyroid disease or current radioactive iodine treatment 3. Lithium therapy 4. Known pregnancy 5. Renal failure

Design outcomes

Primary

Measure	Time frame
Salivary CT values of SARS CoV-2 is measured using reverse-transcription polymerase chain reaction (RT-PCR) at baseline, 5 min, 3 hours and 6 hours	—

Secondary

Measure	Time frame
There are no secondary outcome measures	—

Countries

Indonesia

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026