Depression Mental and Behavioural Disorders Depression
Conditions
Interventions
Continuation anti-depressants or Mindfulness-based Cognitive Therapy.
Sponsors
University of Exeter (UK)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Three or more previous episodes of depression meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria (including the current episode) 2. Aged 18 or older 3. Currently in either partial or full remission from last episode of depression
Exclusion criteria
Exclusion criteria: Co-morbid psychiatric diagnoses that would: 1. Interfere with engaging with MBCT (current substance dependence) 2. Be exacerbated by MBCT (psychosis, very disabling obsessive compulsive disorder) and formal concurrent psychotherapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In line with previous MBCT randomised controlled trials (RCTs), the primary outcome measure will be a recurrence of depression meeting DSM-IV criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures will be residual depressive symptoms (measured by the interviewer-rated Hamilton Depression Scale and self-report Beck Depression Inventory). In line with effectiveness trials examining an intervention?s generalisability, a novel feature of this study will be extending outcome assessment to health status (using the Medical Outcomes Study [MOS SF-12] instrument), quality of life (using the World Health Organisation Quality of Life [WHOQOL-BREF] instrument), and health costs (using Client Service Receipt Inventory adapted for depression relapse studies). | — |
Countries
United Kingdom
Outcome results
None listed