Primary osteoporosis Musculoskeletal Diseases
Conditions
Interventions
This is a four-arm, parallel-group, randomised, single-blind assessor-blinded controlled trial. A total of 168 participants with primary osteoporosis will be randomly allocated in a 1:1:1:1 ratio to o
(2) medium-frequency Baduanjin group: supervised Baduanjin exercise 3 sessions per week, at least 60 minutes per session
(3) low-frequency Baduanjin group: supervised Baduanjin exercise 1 session per week, at least 60 minutes per session
(4) control group: usual daily activities without structured Baduanjin exercise.
The randomisation sequence will be generated by an independent statistician using R software, version 4.5.1. Allocation
Sponsors
China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of primary osteoporosis (DXA T-score = -2.5 at lumbar spine, total hip or femoral neck, or presence of a hip/vertebral fragility fracture) 2. Aged 50–79 years, any sex 3. Berg Balance Scale score between 22 and 51 4. Able to give informed consent and voluntarily participate
Exclusion criteria
Exclusion criteria: 1. Secondary osteoporosis (e.g., due to hyperparathyroidism, long-term glucocorticoid use, rheumatoid arthritis, etc.) 2. Use of anti-osteoporosis prescription medication (bisphosphonates, denosumab, teriparatide, selective estrogen receptor modulators, etc.) within 6 months prior to enrolment 3. Severe or unstable cardiovascular, respiratory or neurological disease (e.g., uncontrolled hypertension = 160/100 mmHg, heart failure, stroke sequelae) 4. Severe knee, hip or spinal conditions that prevent standing or slow walking (e.g., severe osteoarthritis, acute lumbar disc herniation, spinal deformity) 5. Fragility fracture or orthopaedic surgery within the last 3 months 6. Pregnancy, breastfeeding, or planning to become pregnant within the next year 7. Currently engaged in regular exercise (moderate-intensity or above, =3 times per week, =30 minutes each session, including Baduanjin, Tai Chi, brisk walking, jogging, etc.) 8. Concurrent participation in another clinical trial that may affect balance or bone metabolism, or participation in another interventional clinical trial within the last 3 months 9. Unable to use a smartphone (if required for follow-up reminders or questionnaires) 10. Any factors that may limit adherence to follow-up, such as plan to leave the local area for a long time, alcohol or substance abuse, dementia or cognitive impairment
Countries
China
Contacts
Public ContactChuanrui Sun
Outcome results
None listed