Generalized anxiety disorder Mental and Behavioural Disorders
Conditions
Interventions
After receiving an appropriate diagnosis and completing the ethics procedures, participants will be randomly assigned to one of the following two conditions:
1. CBT delivered in face-
Sponsors
University of Quebec at Outaouais (Université du Québec en Outaouais (UQO)) (Canada)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ambulatory man and woman 2. At least 18 years old and at most 75 years old 3. French speaking 4. Receiving a principal diagnosis of GAD based on DSM-5 diagnostic criteria. Assessed with asemi-structured diagnostic interview (ADIS) 5. If currently taking medication for GAD, pharmacotherapy must me stabilized (same type and dosage) for at least six months and the GAD remained stable and uncured (i.e. still meeting the diagnostic criteria). Note that there is no perfect solution to the problem of medication since most severe cases already receive Selective Serotonin Reuptake Inhibitor (SSRI) from their doctors when they seek psychological treatments (thus, recruiting non-medicated participants would threaten the feasibility of the study and could lead to the selection of less severe cases) and stopping medication would induce other methodological problems (e.g., withdrawal symptoms, artificial peak of severity at pre-treatment, ethical issues)
Exclusion criteria
Exclusion criteria: 1. Having a principal diagnosis other than GAD 2. Currently suffering from a severe organic disease, dementia, mental retardation, schizophrenia, amnesia, substance abuse, borderline personality disorder, psychosis or bipolar disorder 3. GAD being secondary to a medical condition 4. Active suicidal ideations 5. Starting a new medication or changing actual medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of GAD symptoms on the Anxiety Disorders Interview Schedule (ADIS): The ADIS is a semi-structured interview rating the severity of each symptoms of GAD to provide a global severity rating. It is a common outcome measure in research on GAD. Inter-rater reliability will be assessed and maintained during the entire study. Total score varies between 0 to 8. The ADIS will be administered at baseline, post-treatment and at the 6- and 12-month follow-ups. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Penn-State Worry Questionnaire: This self-report measures signs of GAD and the tendency to worry. The subject must indicate to which degree he or she agrees with 16 assertions typical people suffering from GAD. All items are rated on a 0 to 5 scale. 2. Worry and Anxiety Questionnaire: This questionnaire is a self-rating of the severity of DSM-5?s GAD symptoms measured by the ADIS. All symptoms are rated on a 0 to 8 scale. 3. Intolerance of Uncertainty: Participants rate 45 items assessing the core psychological mechanism of GAD, namely intolerance of uncertainty. This fear of uncertainty is the reason motivating patients to engage in ruminations and worries in order to anticipate and protect themselves from dreaded consequences of daily stressors. All items are rated on a 0 to 5 scale. All outcomes will be assessed at baseline, post-treatment and at the 6- and 12-month follow-ups. | — |
Countries
Canada
Outcome results
None listed