SurOL: Surgery for oral leukoplakia (a white patch in the mouth)

A randomized no intervention-controlled trial of surgery in oral leukoplakia with no dysplasia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ISRCTN

Registry ID

ISRCTN12617344

Enrollment

300

Registered

2019-11-28

Start date

2012-01-01

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral leukoplakia with no signs of dysplasia Digestive System Oral leukoplakia

Interventions

Consecutive Caucasian patients, attending the Oral Medicine Section of the Department of Surgical Sciences, Turin Hospital, Italy, from January 2012 and December 2013, are selected for the present stu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Caucasian patients, attending the Oral Medicine Section of the Department of Surgical Sciences, Turin Hospital 2. Diagnosis of oral leukoplakia with no signs of dysplasia 3. Adults aged 18 and older

Exclusion criteria

Exclusion criteria: 1. Patients with a previous diagnosis of oral cancer. 2. Pregnant or lactating females; patients with incapacity to understand verbal and written instructions

Design outcomes

Primary

Measure	Time frame
Malignant transformation of the biopsied lesion measured using visual inspection by a physician every six months	—

Secondary

Measure	Time frame
Progression of the disease measured using visual inspection by a physician every six months	—

Countries

Italy

Contacts

Public ContactPaolo G Arduino

paologiacomo.arduino@unito.it00390116331522

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026