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Accelerating tooth movement with platelet-rich plasma

Enhancing orthodontic treatment efficiency with platelet-rich plasma: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ISRCTN
Registry ID
ISRCTN12537093
Enrollment
40
Registered
2024-08-27
Start date
2022-01-01
Completion date
Unknown
Last updated
2024-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior teeth crowding Oral Health

Interventions

Patients were randomly assigned to either the PRP group or the control group. The PRP group received PRP injections at 0, 7, and 14 days, while the control group received standard orthodontic treatmen

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Eligible participants were individuals aged 18 to 25 years 2. The study focused on patients with anterior teeth crowding ranging from 3 to 6 mm 3. A prerequisite for inclusion was the maintenance of excellent oral hygiene and periodontal status 4. Candidates with no prior orthodontic treatment history were included

Exclusion criteria

Exclusion criteria: 1. Individuals with any systemic medical conditions were not considered for the study 2. Excluded were patients with dental anomalies in tooth size or shape 3. The study did not include patients with skeletal discrepancies in the vertical, transverse, or anteroposterior dimensions 4. Those currently taking anti-inflammatory medications were also excluded from participation

Design outcomes

Primary

MeasureTime frame
Little’s Irregularity Index: Dental models were obtained at four key stages: initial (T0), 5 weeks after beginning treatment (T1), 8 weeks into treatment (T2), and 10 weeks into treatment (T3). The Little’s Irregularity Index was calculated with precision using a digital caliper to measure the distances between the contact points of the six anterior maxillary teeth.

Secondary

MeasureTime frame
The duration of the orthodontic treatment was recorded in months, starting with the bonding of 0.022-inch brackets and concluding with the application of a 0.017 x 0.025-inch stainless steel archwire.

Countries

Syria

Contacts

Public ContactMay Akel
drmayakel@gmail.com+963 992964458

Outcome results

None listed

Source: ISRCTN (via WHO ICTRP) · Data processed: Feb 4, 2026